The Red Wings lost to the Penguins 6-3 Thursday night in Pittsburgh.
Tomas Jurco, Dylan Larkin and Henrik Zetterberg scored for Detroit.
Petr Mrazek was pulled in the third period after stopping 26 of the 31 shots.
Jimmy Howard closed out the game with six saves.
The Wings continue their four game road trip against the Senators in Ottawa Saturday.
Washington Capitals 3, New York Islanders 2 (OT)
Pittsburgh Pengiuns 6, Detroit Red Wings 3
New York Rangers 4, Toronto Maple Leafs 2
Ottawa Senators 4, Carolina Hurricanes 2
Tampa Bay Lightning 6, Winnipeg Jets 5 (SO)
San Jose Sharks 2, Florida Panthers 1 (SO)
St. Louis Blues 2, Los Angeles Kings 1 (OT)
Nashille Predators 2, Boston Bruins 0
Minnesota Wild 5, Edmonton Oilers 2
Phoenix Coyotes 6, Dallas Stars 3
Anaheim Ducks 5, Vancouver Canucks 2
By: Mike Plourde – for Great Lakes Radio Sports